MSC Culture Supernatant to Prevent Diseases

StemSup® is the supernatant of MSC culture. MSCs are cultured in a specific manner so that they secrete a lot of active substances, which include over a hundred kinds of cytokines as well as exosomes that contain microRNAs.

The cytokines and exosomes in StemSup® can serve as messengers to control cellular growth, improve blood flow, and suppress inflammation at the site of tissue injury in your body. This feature of StemSup® should prevent aggravation of tissue damage or progression to active disease, and help you stay healthy.


StemSup® contains only natural substances secreted by MSCs to minimize the risk of undesirable reactions. No artificial ingredients such as cytokines, insulin, and fetal bovine serum are added to StemSup®.


Choosing a StemSup® Platform that Best Suits Your Need

There are three types of StemSup®; StemSup-A, StemSup-DP and StemSup-UC. StemSup-A is generated using adipose-derived MSCs. StemSup-DP is generated using MSCs in the dental pulp of deciduous tooth. StemSup-UC is generated using umbilical cord-derived MSCs. Each type of StemSup has a unique profile of active substances. Therefore, you can choose the type of StemSup® that is the most suitable for relieving your symptoms.


Moreover, StemSup® can be used by multiple routes of administration.

Intravenous Infusion

By administering StemSup® via intravenous infusion, active substances are delivered through blood stream. This way of administration of StemSup® seems good for treating liver dysfunction, fatigue, neuralgia, stiff shoulders, insomnia (sleeplessness), visual disturbance, cold constitution, and menopausal symptoms.


Nasal Spray

By administering StemSup® to the nasal cavity using a nasal spray, active substances can get into the cerebrospinal fluid and affect the brain function. This way of administration has therapeutic potential in treating cerebral infarction sequelae, cognitive impairment, spinal cord injury, and cerebral palsy. You can perform the nasal spray maneuver by yourself at home with regular medical follow-up at Tokyo Clinic.


Local Injection

StemSup® can be injected directly into the skin for skin rejuvenation; improving skin texture and reducing facial wrinkles, e.g., nasolabial folds. Furthermore, StemSup® can be injected directly into the scalp to promote hair growth.


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